WebSep 9, 2016 · Introduction: Serum protein electrophoresis (SPEP) is used to detect monoclonal gammopathies (M-proteins), though some M-proteins are too low in concentration and require immunofixation (IFE) for detection. Consequently, interpreters of SPEP use various clues to determine when to reflex an SPEP for IFE. … WebAug 23, 2024 · The M-protein spike detected by UPEP or SPEP is actually made up of monoclonal light chains, so they definitely can detect light chains. IFE on the other hand …
(PDF) Gamma heavy chain disease in a patient with diabetes and …
WebJan 24, 2024 · Serum protein electrophoresis (SPEP) is a laboratory technique that’s used to determine the levels of some types of proteins in a blood sample. There are a number of reasons why a doctor may... WebAug 15, 2024 · Screening SPEP with immunofixation (IFE) is a widely recommended part of the initial evaluation of patients with peripheral neuropathy. [6, 7] SPEP is a quantitative test which is commonly used and widely available, however it has limited sensitivity and cannot distinguish a monoclonal isotype. IFE, in contrast, is qualitative and more ... iphone 6s backup file exts
Relationship between monoclonal gammopathy and cardiac amyloid …
WebIf screening for plasma cell dyscrasias, the International Myeloma Working Group recommends a screening panel consisting of serum free light chain assay, serum protein … http://connectioncenter.3m.com/protein+electrophoresis+lab+report WebMASS-FIX's ability to verify abnormal results from SPEP and free light chain measurements was then compared with that of immunofixation electrophoresis (IFE) using a separate cohort of 52,586 patients tested by SPEP/IFE during the same period. Results: Overall, 62.4% of our cohort was negative for an M-protein. Importantly, 7.3% of all ... iphone 6s back camera repair mother