Web(21) YTHDF2 ablation increases the stability of the TNFRSF 2 mRNA, which sensitizes LSCs to TNF-induced apoptosis, suggesting that inhibition of YTHDF2 could be … WebMDM2 Antibody (33-7100) in ICC/IF. Immunofluorescence analysis of MDM2 in subconfluent U2OS cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, …
YTHDF2 - Wikipedia
WebAs the most abundant and conserved internal modification in eukaryote RNAs, N6-methyladenosine (m6A) is involved in a wide range of physiological and pathological … Web21 nov. 2014 · YTHDF2 consists of a C-terminal YTH domain (designated as YTH YTHDF2), which specifically binds to m 6 A-containing RNA (m 6 A-RNA) with a preference for … scientific integrity officer
Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with …
Web31 jul. 2024 · As YTHDF2 is a well-recognized m 6 A “reader” that mediates mRNA decay, 30 we determined its targets by performing infrared UV-crosslinking immunoprecipitation … Web13 apr. 2024 · (A) METTL3, YTHDF2, and YTHDC1 were knocked down in A549 cells by shRNA, and then infected with the PR8 virus. Virus titer and protein expression were detected by TCID 50 and western blotting at 24 hpi (left). Each protein band was quantified by ImageJ and normalized to GAPDH levels (right). Web29 dec. 2024 · While recent work addressed the role of Ythdf2 in the zebrafish MZT (Zhao et al., 2024), we sought to establish the effects of m 6 A on maternal transcripts directly, … scientific integrity example