Ferroptotic 翻译
Web铁反应元件( iron re-sponse element, IRE)是一段特别的mRNA序列,具二级结构可影响蛋白的翻译,IRP与 TfR1 mRNA 上的3′端 IRE 结合后,可稳定这段mRNA,使其翻译出更多的转铁蛋白受体。 WebAstragaloside IV (AsIV), an active ingredient isolated from traditional Chinese medicine astragalus membranaceus, is beneficial to cardiovascular health. This study aimed to characterize the functional role of AsIV against adriamycin (ADR)-induced cardiomyopathy. Here, healthy rats were treated with …
Ferroptotic 翻译
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WebGoogle 免费提供的这项服务可在简体中文和其他 100 多种语言之间即时翻译字词、短语和网页。 WebAug 9, 2024 · Understanding how cancer cells resist ferroptosis is a significant problem that impacts ongoing efforts to stimulate ferroptosis as a therapeutic strategy. We reported that prominin2 is induced by ferroptotic stimuli and functions to resist ferroptotic death. Although this finding has significant im …
Webフェロトーシス(ferroptosis)は、鉄に依存し、過酸化脂質の蓄積によって特徴付けられるプログラム細胞死の一種であり、アポトーシスなどの他の制御された細胞死とは遺伝学的にも生化学的にも異なる 。 フェロトーシスは、グルタチオン依存的な抗酸化防御の破綻によって始まり、脂質の過 ... WebNov 19, 2024 · Regulation of Ferroptotic Cancer Cell Death by GPX4. 本选自cell 2013年老文章. 摘要:铁死亡是一种非凋亡细胞死亡形式,其关键调节因子尚不清楚。我们为12种 …
Web刘华元 史光军 [摘要] 铁死亡是一种以细胞内铁依赖的脂质过氧化物蓄积为特征的细胞死亡方式,它与细胞典型的坏死、凋亡和自噬不同,在形态学、生物化学和遗传学上具有独特性。
WebJul 19, 2024 · Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in maladaptive renal repair in mice and humans. Using single-cell transcriptomic and mouse genetic approaches, we show that proximal tubular (PT) cells develop a molecularly distinct, pro-inflammatory ...
WebMay 27, 2024 · Ferroptotic cell death can often interact with immunity through complicated cellular–molecular mechanisms in multiple ways. Firstly, ferroptotic cells can release danger signals like damage-associated molecular patterns (DAMPs) or metabolites that may serve as messengers to surrounding immune cells []. The released signal can be either ... brinckmann group apsWeb2024-03-26报道,近日,中国医科大学的研究者们在Trends in Molecular Medicine杂志上发表了题为“Ferroptosis in Parkinson’s disease:glia–neuron crosstalk”的综述性文章,本综述研究了不同类型的胶质细胞在调节神经元铁性死亡中的可能作用。. 最后,研究者回顾了目前针 … brinckman rapportWebSince ferroptosis participates in the progression of metabolic diseases such as non-alcoholic steatohepatitis (NASH), there is a need to develop new drugs targe …. … can you pay with card on weedmapsWebDec 2, 2024 · Ferroptotic cell death can lead to different immune and inflammatory reactions through the release and activation of damage-associated molecular patterns (e.g., HMGB1 and DNA) or lipid oxidation products (e.g., 4HNE, oxPLs, LTB4, LTC4, LTD4, and PGE2) in immune cells (e.g., macrophages, monocytes, and neutrophils) via different … can you pay with cash appWebFeb 21, 2024 · In this study, we found that ferroptotic stress can help macrophages suppress intracellular bacteria by reversing the importation of ferrous iron into bacterial vacuoles via ferroportin and thereby inducing in situ ferroptosis-like bacterial death. Methods: A macrophage model of bacterial invasion was established to monitor dynamic … can you pay wips onlineWebJan 21, 2024 · Ferroptotic response can be fine-tuned through various oxidative stress and antioxidant defense pathways, coupling with metabolism, gene transcription, and protein degradation machinery. Accordingly, a series of ferroptosis inducers or inhibitors targeting redox- or iron metabolism-related proteins or signal transduction have been developed. can you pay with apple cashWebAug 31, 2024 · Fig. 1: Cell–cell propagation of ferroptosis is a distinct step from ferroptotic cell lysis. (1) Increasing cellular lipid peroxidation induces ferroptosis. (2) This can initiate a chain ... can you pay with cashapp on amazon