Ferrophagy
Tīmeklis2010. gada 1. febr. · In recent studies, nuclear receptor coactivator 4 (NCOA4)-mediated ferrophagy has been shown to induce iron release from ferritin. ... Ferroptosis: Can Iron be the Last or Cure for a Cell? Tīmeklis2014. gada 30. marts · Request PDF Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy Autophagy, the process by which proteins …
Ferrophagy
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TīmeklisFerroptosis is one of the forms of programmed cell death. Besides being a necessary micronutrient, iron is the key element that initiates ferroptosis in the cell. Intracellular unstable iron accumulation increases the amount of intracellular ROS, especially by the peroxidation of unsaturated membrane phospholipids. Insufficient antioxidant … Tīmeklis2024. gada 3. dec. · These effects are recovered by supplying iron via a lysosome-independent pathway. Notably, iron deficiency is sufficient to trigger inflammatory …
Tīmeklis2014. gada 1. maijs · Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and delivered … Tīmeklis2024. gada 4. apr. · Dr. Alex Mercer wakes up having gained powers but lost his memory, and is thrust into a world where heroes and villains are a deadly reality. Aspiring superhero Taylor Hebert mistakes Alex for a Case 53 and tries to help, but hides the fact that she can control his hive-mind of wormlike...
Tīmeklis2024. gada 3. aug. · Subsequent inflammation caused by the Interlukin-6 response triggers a hepcidin surge which decreases the expression of Ferroportin and increases the ferrophagy via Transferrin 1 receptor ... Tīmeklis2008. gada 1. maijs · The normal, low-level diffusion of hydrogen peroxide into iron-rich lysosomes causes the slow formation of lipofuscin in long-lived postmitotic cells, …
Tīmeklis2006. gada 1. marts · Periodontitis is a chronic inflammatory disease affecting oral tissues. The continuous, high production of cytokines by host cells triggered by …
Tīmeklis2015. gada 5. okt. · NCOA4 is a selective cargo receptor for the autophagic turnover of ferritin, a process critical for regulation of intracellular iron bioavailability. However, … lehigh computer programsTīmeklis2016. gada 12. aug. · Ferroptosis is an iron-dependent form of regulated necrosis. It is implicated in various human diseases, including ischemic organ damage and cancer. … lehigh conduct caseshttp://www.desformx.org/79693.html lehigh conference of churches pathwaysTīmeklis2024. gada 30. apr. · The importance of the role of iron regulatory proteins (IRPs) in mitochondrial iron homeostasis and function has been raised. To understand how an … lehigh conference of churches rep payeelehigh conference of churches case managementTīmeklis2024. gada 2. apr. · Unexpectedly, a concentrated sample of highly purified FBXL5C492Δ was brown in color (Figure 1 C), suggesting the presence of an iron … lehigh connect alumniTīmeklis2024. gada 1. jūl. · Ferroptosis contributes to the onset or progression of various metabolic diseases. Ferritinophagy is a selective type of autophagy, which induces … lehigh conservation